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NUDT11 Antibody, FITC conjugated

Datasheet
Code CSB-PA836216LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) NUDT11 Polyclonal antibody
Uniprot No.
Q96G61
Target Names
NUDT11
Alternative Names
NUDT11 antibody; APS1 antibody; DIPP3BDiphosphoinositol polyphosphate phosphohydrolase 3-beta antibody; DIPP-3-beta antibody; DIPP3-beta antibody; hDIPP3beta antibody; EC 3.6.1.52 antibody; Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 3-beta antibody; Diadenosine hexaphosphate hydrolase antibody; AMP-forming) antibody; EC 3.6.1.60 antibody; Nucleoside diphosphate-linked moiety X motif 11 antibody; Nudix motif 11 antibody; hAps1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Diphosphoinositol polyphosphate phosphohydrolase 3-beta protein (1-164AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate.
Gene References into Functions
  1. NUDT11, HNF1B, and SLC22A3 genes have roles in prostate cancer pathogenesis PMID: 22730461
  2. The NUDT11 gene, located on chromosome X, is preferentially expressed in the testis PMID: 12105228
  3. Cloning and characterisation of NUDT11 as a diadenosine polyphosphate-metabolising Nudix hydrolase. PMID: 12121577
Subcellular Location
Cytoplasm.
Protein Families
Nudix hydrolase family, DIPP subfamily
Tissue Specificity
Mainly expressed in testis and, at lower level in brain. According to PubMed:12121577, it is also expressed in pancreas and weakly expressed in thymus, prostate, ovary, lung, small intestine and heart.
Database Links

HGNC: 18011

OMIM: 300528

KEGG: hsa:55190

STRING: 9606.ENSP00000365160

UniGene: Hs.200016

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